Development of A Noninvasive Blood Glucose Monitoring System Prototype…
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작성자 ZJ 작성일25-08-11 03:27 (수정:25-08-11 03:27)관련링크
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Background: Diabetes mellitus is a extreme illness characterized by excessive blood glucose levels resulting from dysregulation of the hormone insulin. Diabetes is managed through bodily exercise and dietary modification and requires cautious monitoring of blood glucose focus. Blood glucose focus is often monitored throughout the day by analyzing a pattern of blood drawn from a finger prick utilizing a commercially available glucometer. However, this course of is invasive and painful, and leads to a threat of infection. Therefore, there may be an pressing want for noninvasive, inexpensive, novel platforms for continuous blood sugar monitoring. Objective: Our research aimed to describe a pilot check to check the accuracy of a noninvasive glucose monitoring prototype that makes use of laser expertise based mostly on near-infrared spectroscopy. Methods: Our system relies on Raspberry Pi, a portable camera (Raspberry Pi digicam), BloodVitals SPO2 device and a visible mild laser. The Raspberry Pi digicam captures a set of pictures when a visible gentle laser passes through skin tissue. The glucose concentration is estimated by an artificial neural community model utilizing the absorption and scattering of mild within the skin tissue.
This prototype was developed utilizing TensorFlow, Keras, and Python code. A pilot research was run with 8 volunteers that used the prototype on their fingers and ears. Blood glucose values obtained by the prototype had been in contrast with commercially obtainable glucometers to estimate accuracy. Results: When using photos from the finger, the accuracy of the prototype is 79%. Taken from the ear, the accuracy is attenuated to 62%. Though the present information set is proscribed, these outcomes are encouraging. However, three foremost limitations should be addressed in future studies of the prototype: (1) enhance the scale of the database to enhance the robustness of the artificial neural community mannequin; (2) analyze the affect of exterior factors akin to skin colour, skin thickness, and ambient temperature in the current prototype; and (3) enhance the prototype enclosure to make it appropriate for simple finger and ear placement. Conclusions: Our pilot research demonstrates that blood glucose concentration could be estimated using a small hardware prototype that makes use of infrared pictures of human tissue.
Although extra studies must be performed to beat limitations, this pilot research shows that an reasonably priced device can be utilized to keep away from the use of blood and multiple finger pricks for blood glucose monitoring within the diabetic population. Successful management of diabetes entails monitoring blood glucose ranges multiple occasions per day. This device determines glucose focus from a droplet of blood obtained from a finger prick or a laboratory blood draw. Therefore, noninvasive methods are a pretty various, nevertheless, people who are available at this time have several limitations. Figure 1 illustrates an example of each kind of noninvasive and minimally invasive blood glucose monitoring. These devices have the benefit of being both portable and cheap. Here, we describe the event of a novel noninvasive glucose monitoring system that makes use of the computing energy of sensors and BloodVitals health Internet of Things gadgets to constantly analyze blood glucose from a microcomputer and a sensor embedded within a clip positioned on the finger or ear. The prototype makes use of infrared spectroscopy to create photos of the rotational and vibrational transitions of chemical bonds within the glucose molecule, and incident gentle reflection to measure their corresponding fluctuation.
The images are converted into an array record, BloodVitals health which is used to provide entries for BloodVitals health an synthetic neural network (ANN) to create an estimate of blood glucose focus. The prototype is simple to make use of and is paired with a mobile app free of charge-residing environments. Figure 2 exhibits an overview of the proposed system. I0 is the preliminary gentle intensity (W/cm2), I is the depth of the ith at any depth inside the absorption medium in W/cm2, l is the absorption depth within the medium in centimeters, e is the molar extinction coefficient in L/(mmol cm), and c is the focus of absorbing molecules in mmol/L. The product of and BloodVitals device c is proportional to the absorption coefficient (µa). The concentration of absorbing molecules relies on the above equation. However, BloodVitals tracker the effect of different blood parts and absorbing tissue parts affects the quantity of mild absorbed. Then, to attenuate the absorption attributable to all the other elements, the wavelength of the light source ought to be chosen in order that the light supply is extremely absorbed by glucose and is mostly clear to blood and tissue components.
Although the Raspberry Pi digital camera captures photographs, a laser mild captures absorption. A small clip that can be positioned on a finger or earlobe holds the laser on the top half and the camera on the bottom. Figure three depicts the elements of the prototype (Raspberry Pi, digital camera, and laser gentle). The prototype has been named GlucoCheck. The Raspberry Pi digital camera captures one image each eight seconds over 2 minutes, for a total of 15 images. Brightness and distinction ranges are set to 70 cycles/diploma, digicam ISO sensitivity is ready to 800, and BloodVitals SPO2 decision is about to 640 × 480. Figures 4 and 5 present the prototype connected to the finger and ear, BloodVitals health respectively. The supplies for the GlucoCheck prototype price approximately US $79-$154 in 2022, BloodVitals health relying on the availability of chips, which has been an ongoing situation in current months. Typically, computer boards are plentiful, however 2022 noticed a shortage of chips, leading to inflated prices compared to previous years.
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